Urinary Tract Infections and Antimicrobial Resistance: Analysis of Pathogen Prevalence and Treatment Efficacy at Al Manar Laboratory in Derna City

Abstract

Abstract: This study investigates the prevalence and antibiotic sensitivity of bacterial pathogens responsible for urinary tract infections (UTIs) in patients at Al Manar Laboratory. Data were collected from 51 patients, comprising 44 women and 7 men, aged 15 to 45 years, over a one-month period. The study aimed to identify the bacterial species causing UTIs, assess the effectiveness of various antibiotics, and explore the relationship between gender and infection rates. The findings revealed a significant gender disparity, with 86.27% of UTI cases occurring in females. Staphylococcus aureus and Escherichia coli were the most prevalent pathogens, accounting for 39.21% and 35.29% of the infections, respectively. Antibiotic sensitivity testing showed that Meropenem was the most effective treatment for both S. aureus and E. coli, with sensitivity rates of 93.75% and 100%, respectively. In contrast, other antibiotics like Trimethoprim-Sulfamethoxazole and Clindamycin demonstrated low sensitivity, indicating significant resistance. The study underscores the importance of targeted antibiotic therapy based on sensitivity testing to combat antimicrobial resistance and improve treatment outcomes for UTIs. Additionally, it highlights the need for tailored prevention strategies, particularly for women, who are disproportionately affected by UTIs.